Genome editing tools for improved and sustainable livestock production systems

Authors

  • Shweta Yadav Embryo Biotechnology Lab, Animal Biotechnology Division, ICAR-National Dairy Research Institute, Karnal, India-132001 Author
  • Priyanka Singh Embryo Biotechnology Lab, Animal Biotechnology Division, ICAR-National Dairy Research Institute, Karnal, India-132001 Author
  • Manoj Kumar Singh Embryo Biotechnology Lab, Animal Biotechnology Division, ICAR-National Dairy Research Institute, Karnal, India-132001 Author
  • Naresh L. Selokar Embryo Biotechnology Lab, Animal Biotechnology Division, ICAR-National Dairy Research Institute, Karnal, India-132001 Author

DOI:

https://doi.org/10.59317/tk0rpj66

Keywords:

Genome editing, Livestock, Improved production, Disease resistance, Climate resilience, Regulatory framework

Abstract

Genome editing has great potential to improve production traits such as dairy and meat quality, as well as wool production in livestock species. Some notable examples include the production of the β-lactoglobulin (BLG) knockout resulting in hypoallergenic milk, disruption of the myostatin (MSTN) gene leading to increased muscle mass, longer wool achieved by mutating the fibroblast growth factor 5 (FGF5) gene, and the development of porcine reproductive and respiratory syndrome (PRRS)-resistant pigs through the editing of the CD163 receptor. These advancements demonstrated the immense potential for enhancing productivity, animal health, and welfare to significant impact the economic benefits for farmers and industries. The regulatory landscape for gene-edited animals varies globally; the countries like Argentina, Australia, Brazil, Colombia, and Japan have adopted progressive policies by treating gene- edited animals similarly to those produced by conventional breeding. In conclusion, genome editing technologies have the potential to transform agriculture, promoting sustainability and efficiency in livestock production systems.

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Published

18-11-2024

How to Cite

Genome editing tools for improved and sustainable livestock production systems. (2024). The Indian Journal of Animal Genetics and Breeding, 43(1,2), 95-100. https://doi.org/10.59317/tk0rpj66

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